Evaluation of whole genome amplification and bioinformatic methods for the characterization of Leishmania genomes at a single cell level

Here, we report a pilot study paving the way for further single cell genomics studies in Leishmania. First, the performances of two commercially available kits for Whole Genome Amplification (WGA), PicoPLEX and RepliG were compared on small amounts of Leishmania donovani DNA, testing their ability t...

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Detalles Bibliográficos
Autores principales: Imamura, Hideo, Monsieurs, Pieter, Jara, Marlene, Sanders, Mandy, Maes, Ilse, Vanaerschot, Manu, Berriman, Matthew, Cotton, James A., Dujardin, Jean-Claude, Domagalska, Malgorzata A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490275/
https://www.ncbi.nlm.nih.gov/pubmed/32929126
http://dx.doi.org/10.1038/s41598-020-71882-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490275/
https://www.ncbi.nlm.nih.gov/pubmed/32929126
http://dx.doi.org/10.1038/s41598-020-71882-2

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