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Evaluation of whole genome amplification and bioinformatic methods for the characterization of Leishmania genomes at a single cell level
Here, we report a pilot study paving the way for further single cell genomics studies in Leishmania. First, the performances of two commercially available kits for Whole Genome Amplification (WGA), PicoPLEX and RepliG were compared on small amounts of Leishmania donovani DNA, testing their ability t...
Autores principales: | Imamura, Hideo, Monsieurs, Pieter, Jara, Marlene, Sanders, Mandy, Maes, Ilse, Vanaerschot, Manu, Berriman, Matthew, Cotton, James A., Dujardin, Jean-Claude, Domagalska, Malgorzata A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490275/ https://www.ncbi.nlm.nih.gov/pubmed/32929126 http://dx.doi.org/10.1038/s41598-020-71882-2 |
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