IL-20 antagonist suppresses PD-L1 expression and prolongs survival in pancreatic cancer models

Pancreatic ductal adenocarcinoma (PDAC) and cancer-associated cachexia (CAC) are multifactorial and characterized by dysregulated inflammatory networks. Whether the proinflammatory cytokine IL-20 is involved in the complex networks of PDAC and CAC remains unclear. Here, we report that elevated IL-20...

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Detalles Bibliográficos
Autores principales: Lu, Shao-Wei, Pan, Hong-Chin, Hsu, Yu-Hsiang, Chang, Kung-Chao, Wu, Li-Wha, Chen, Wei-Yu, Chang, Ming-Shi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490368/
https://www.ncbi.nlm.nih.gov/pubmed/32929072
http://dx.doi.org/10.1038/s41467-020-18244-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490368/
https://www.ncbi.nlm.nih.gov/pubmed/32929072
http://dx.doi.org/10.1038/s41467-020-18244-8

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