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Analysis of the SARS-CoV-2 spike protein glycan shield reveals implications for immune recognition

Here we have generated 3D structures of glycoforms of the spike (S) glycoprotein from SARS-CoV-2, based on reported 3D structures and glycomics data for the protein produced in HEK293 cells. We also analyze structures for glycoforms representing those present in the nascent glycoproteins (prior to e...

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Detalles Bibliográficos
Autores principales: Grant, Oliver C., Montgomery, David, Ito, Keigo, Woods, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490396/
https://www.ncbi.nlm.nih.gov/pubmed/32929138
http://dx.doi.org/10.1038/s41598-020-71748-7