Impact of Sustained Transforming Growth Factor-β Receptor Inhibition on Chromatin Accessibility and Gene Expression in Cultured Human Endometrial MSC

Endometrial mesenchymal stem cells (eMSC) drive the extraordinary regenerative capacity of the human endometrium. Clinical application of eMSC for therapeutic purposes is hampered by spontaneous differentiation and cellular senescence upon large-scale expansion in vitro. A83-01, a selective transfor...

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Detalles Bibliográficos
Autores principales: Lucciola, Raffaella, Vrljicak, Pavle, Gurung, Shanti, Filby, Caitlin, Darzi, Saeedeh, Muter, Joanne, Ott, Sascha, Brosens, Jan J., Gargett, Caroline E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490520/
https://www.ncbi.nlm.nih.gov/pubmed/32984350
http://dx.doi.org/10.3389/fcell.2020.567610

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490520/
https://www.ncbi.nlm.nih.gov/pubmed/32984350
http://dx.doi.org/10.3389/fcell.2020.567610

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