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Pak1ip1 Loss-of-Function Leads to Cell Cycle Arrest, Loss of Neural Crest Cells, and Craniofacial Abnormalities

Neural crest cells (NCCs) comprise a transient progenitor cell population of neuroepithelial origin that contributes to a variety of cell types throughout vertebrate embryos including most mesenchymal cells of the cranial and facial structures. Consequently, abnormal NCC development underlies a vari...

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Detalles Bibliográficos
Autores principales: Panoutsopoulos, Alexios A., De Crescenzo, Angelo Harlan, Lee, Albert, Lu, Amelia MacKenzie, Ross, Adam P., Borodinsky, Laura N., Marcucio, Ralph, Trainor, Paul A., Zarbalis, Konstantinos S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490522/
https://www.ncbi.nlm.nih.gov/pubmed/32984348
http://dx.doi.org/10.3389/fcell.2020.510063