Effects of perfluoroalkyl carboxylic acids on the uptake of sulfobromophthalein via organic anion transporting polypeptides in human intestinal Caco-2 cells

We performed a detailed investigation of the uptake of sulfobromophthalein (BSP) from the apical membrane of Caco-2 cells, which is a substrate for organic anion transporting polypeptides (OATPs), and calculated the kinetic parameters of BSP uptake as follows: K(m) = 13.9 ± 1.3 μM, V(max) = 1.15 ± 0...

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Detalles Bibliográficos
Autores principales: Kimura, Osamu, Fujii, Yukiko, Haraguchi, Koichi, Kato, Yoshihisa, Ohta, Chiho, Koga, Nobuyuki, Endo, Tetsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490525/
https://www.ncbi.nlm.nih.gov/pubmed/32964147
http://dx.doi.org/10.1016/j.bbrep.2020.100807

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490525/
https://www.ncbi.nlm.nih.gov/pubmed/32964147
http://dx.doi.org/10.1016/j.bbrep.2020.100807

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