Theaflavin Induces Apoptosis of A375 Human Melanoma Cells and Inhibits Tumor Growth in Xenograft Zebrafishes Through P53- and JNK-Related Mechanism

Theaflavin (TF) is a major active pigment and polyphenol of tea, possessing anti-cancer activities. However, little is known about its activity and mechanism on melanoma cells. To fill this gap, we conducted in vitro experiments (cell viability assay, morphology observation, DAPI staining, and flow...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Lei, Yan, Bo, Meng, Shijie, Zhou, Li, Xu, Yiqiao, Du, Wenxi, Shan, Letian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490558/
https://www.ncbi.nlm.nih.gov/pubmed/32982737
http://dx.doi.org/10.3389/fphar.2020.01317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490558/
https://www.ncbi.nlm.nih.gov/pubmed/32982737
http://dx.doi.org/10.3389/fphar.2020.01317

Ejemplares similares