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Mdivi-1 attenuates oxidative stress and exerts vascular protection in ischemic/hypoxic injury by a mechanism independent of Drp1 GTPase activity
Vascular dysfunctions such as vascular hyporeactivity following ischemic/hypoxic injury are a major cause of death in injured patients. In this study, we showed that treatment with mitochondrial division inhibitor 1 (Mdivi-1), a selective inhibitor of dynamin-related protein 1 (Drp1), significantly...
Autores principales: | Duan, Chenyang, Wang, Li, Zhang, Jie, Xiang, Xinming, Wu, Yue, Zhang, Zisen, Li, Qinghui, Tian, Kunlun, Xue, Mingying, Liu, Liangming, Li, Tao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490562/ https://www.ncbi.nlm.nih.gov/pubmed/32911435 http://dx.doi.org/10.1016/j.redox.2020.101706 |
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