Lentiviral Vector Production from a Stable Packaging Cell Line Using a Packed Bed Bioreactor

Self-inactivating lentiviral vectors (LVVs) are used regularly for genetic modification of cells, including T cells and hematopoietic stem cells for cellular gene therapy. As vector demand grows, scalable and controllable methods are needed for production. LVVs are typically produced in HEK293T cell...

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Detalles Bibliográficos
Autores principales: Powers, Alicia D., Drury, Jason E., Hoehamer, Christopher F., Lockey, Timothy D., Meagher, Michael M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490643/
https://www.ncbi.nlm.nih.gov/pubmed/32995355
http://dx.doi.org/10.1016/j.omtm.2020.08.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490643/
https://www.ncbi.nlm.nih.gov/pubmed/32995355
http://dx.doi.org/10.1016/j.omtm.2020.08.010

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