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Lentiviral Vector Production from a Stable Packaging Cell Line Using a Packed Bed Bioreactor
Self-inactivating lentiviral vectors (LVVs) are used regularly for genetic modification of cells, including T cells and hematopoietic stem cells for cellular gene therapy. As vector demand grows, scalable and controllable methods are needed for production. LVVs are typically produced in HEK293T cell...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society of Gene & Cell Therapy
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490643/ https://www.ncbi.nlm.nih.gov/pubmed/32995355 http://dx.doi.org/10.1016/j.omtm.2020.08.010 |