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Engineered viral DNA polymerase with enhanced DNA amplification capacity: a proof-of-concept of isothermal amplification of damaged DNA

The development of whole genome amplification (WGA) and related methods, coupled with the dramatic growth of sequencing capacities, has changed the paradigm of genomic and genetic analyses. This has led to a continual requirement of improved DNA amplification protocols and the elaboration of new tai...

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Detalles Bibliográficos
Autores principales: Ordóñez, Carlos D., Lechuga, Ana, Salas, Margarita, Redrejo-Rodríguez, Modesto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490695/
https://www.ncbi.nlm.nih.gov/pubmed/32929102
http://dx.doi.org/10.1038/s41598-020-71773-6