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Pathogen-associated selection on innate immunity genes (TLR4, TLR7) in a neotropical rodent in landscapes differing in anthropogenic disturbance

Toll-like receptors (TLRs) form part of the innate immune system and can recognize structurally conserved pathogen-associated molecular pattern (PAMP) molecules. Their functional importance in the resistance to pathogens has been documented in laboratory experimental settings and in humans. TLR dive...

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Detalles Bibliográficos
Autores principales: Heni, Alexander Christoph, Schmid, Julian, Rasche, Andrea, Corman, Victor Max, Drosten, Christian, Sommer, Simone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490709/
https://www.ncbi.nlm.nih.gov/pubmed/32616896
http://dx.doi.org/10.1038/s41437-020-0331-y