Atomic-resolution structure of HIV-1 capsid tubes by magic-angle spinning NMR

HIV-1 capsid plays multiple key roles in viral replication, and inhibition of capsid assembly is an attractive target for therapeutic intervention. Here, we report the atomic-resolution structure of the capsid protein (CA) tubes, determined by magic-angle-spinning NMR and data-guided molecular dynam...

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Detalles Bibliográficos
Autores principales: Lu, Manman, Russell, Ryan W., Bryer, Alex, Quinn, Caitlin M., Hou, Guangjin, Zhang, Huilan, Schwieters, Charles D., Perilla, Juan R., Gronenborn, Angela M., Polenova, Tatyana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490828/
https://www.ncbi.nlm.nih.gov/pubmed/32901160
http://dx.doi.org/10.1038/s41594-020-0489-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490828/
https://www.ncbi.nlm.nih.gov/pubmed/32901160
http://dx.doi.org/10.1038/s41594-020-0489-2

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