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The E3 Ubiquitin Ligase SYVN1 Ubiquitinates Atlastins to Remodel the Endoplasmic Reticulum Network

Atlastin (ATL) is a class of dynamin-like GTPases shaping endoplasmic reticulum (ER) by mediating homotypic membrane fusion. Defect of ATLs leads to abnormal ER structure and hereditary spastic paraplegia (HSP), a neurodegenerative disease with progressive spasticity. How ATLs are regulated to maint...

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Detalles Bibliográficos
Autores principales: Zhao, Yupeng, Feng, Zhigang, Zou, Yan, Liu, Yanfen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490852/
https://www.ncbi.nlm.nih.gov/pubmed/32916628
http://dx.doi.org/10.1016/j.isci.2020.101494