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Independent glial subtypes delay development and extend healthy lifespan upon reduced insulin-PI3K signalling

BACKGROUND: The increasing age of global populations highlights the urgent need to understand the biological underpinnings of ageing. To this end, inhibition of the insulin/insulin-like signalling (IIS) pathway can extend healthy lifespan in diverse animal species, but with trade-offs including dela...

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Detalles Bibliográficos
Autores principales: Woodling, Nathaniel S., Rajasingam, Arjunan, Minkley, Lucy J., Rizzo, Alberto, Partridge, Linda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490873/
https://www.ncbi.nlm.nih.gov/pubmed/32928209
http://dx.doi.org/10.1186/s12915-020-00854-9