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Independent glial subtypes delay development and extend healthy lifespan upon reduced insulin-PI3K signalling
BACKGROUND: The increasing age of global populations highlights the urgent need to understand the biological underpinnings of ageing. To this end, inhibition of the insulin/insulin-like signalling (IIS) pathway can extend healthy lifespan in diverse animal species, but with trade-offs including dela...
Autores principales: | Woodling, Nathaniel S., Rajasingam, Arjunan, Minkley, Lucy J., Rizzo, Alberto, Partridge, Linda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490873/ https://www.ncbi.nlm.nih.gov/pubmed/32928209 http://dx.doi.org/10.1186/s12915-020-00854-9 |
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