Epigenetic regulation of osteopontin splicing isoform c defines its role as a microenvironmental factor to promote the survival of colon cancer cells from 5-FU treatment

BACKGROUND: Drug resistance to 5-fluorouracil (5-FU) and recurrence after chemotherapy in colorectal cancer remain a challenge to be resolved for the improvement of patient outcomes. It is recognized that a variety of secretory proteins released from the tumor cells exposed to chemo-drugs into the t...

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Detalles Bibliográficos
Autores principales: Chang, Siyuan, Huang, Jing, Niu, Huan, Wang, Jing, Si, Yang, Bai, Zhigang, Cheng, Shan, Ding, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7491101/
https://www.ncbi.nlm.nih.gov/pubmed/32944000
http://dx.doi.org/10.1186/s12935-020-01541-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7491101/
https://www.ncbi.nlm.nih.gov/pubmed/32944000
http://dx.doi.org/10.1186/s12935-020-01541-z

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