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The Mechanism of Tubulin Assembly into Microtubules: Insights from Structural Studies

Microtubules are cytoskeletal components involved in pivotal eukaryotic functions such as cell division, ciliogenesis, and intracellular trafficking. They assemble from αβ-tubulin heterodimers and disassemble in a process called dynamic instability, which is driven by GTP hydrolysis. Structures of t...

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Detalles Bibliográficos
Autores principales: Knossow, Marcel, Campanacci, Valérie, Khodja, Liza Ammar, Gigant, Benoît
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7491153/
https://www.ncbi.nlm.nih.gov/pubmed/32920486
http://dx.doi.org/10.1016/j.isci.2020.101511