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The Mechanism of Tubulin Assembly into Microtubules: Insights from Structural Studies
Microtubules are cytoskeletal components involved in pivotal eukaryotic functions such as cell division, ciliogenesis, and intracellular trafficking. They assemble from αβ-tubulin heterodimers and disassemble in a process called dynamic instability, which is driven by GTP hydrolysis. Structures of t...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7491153/ https://www.ncbi.nlm.nih.gov/pubmed/32920486 http://dx.doi.org/10.1016/j.isci.2020.101511 |