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Meta-analysis of transcriptomic variation in T-cell populations reveals both variable and consistent signatures of gene expression and splicing

Human CD4(+) T cells are often subdivided into distinct subtypes, including Th1, Th2, Th17, and Treg cells, that are thought to carry out distinct functions in the body. Typically, these T-cell subpopulations are defined by the expression of distinct gene repertoires; however, there is variability b...

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Detalles Bibliográficos
Autores principales: Radens, Caleb M., Blake, Davia, Jewell, Paul, Barash, Yoseph, Lynch, Kristen W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7491319/
https://www.ncbi.nlm.nih.gov/pubmed/32554554
http://dx.doi.org/10.1261/rna.075929.120