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Molecular basis for the distinct cellular functions of the Lsm1–7 and Lsm2–8 complexes

Eukaryotes possess eight highly conserved Lsm (like Sm) proteins that assemble into circular, heteroheptameric complexes, bind RNA, and direct a diverse range of biological processes. Among the many essential functions of Lsm proteins, the cytoplasmic Lsm1–7 complex initiates mRNA decay, while the n...

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Detalles Bibliográficos
Autores principales: Montemayor, Eric J., Virta, Johanna M., Hayes, Samuel M., Nomura, Yuichiro, Brow, David A., Butcher, Samuel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7491322/
https://www.ncbi.nlm.nih.gov/pubmed/32518066
http://dx.doi.org/10.1261/rna.075879.120