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Inactivation of fission yeast Erh1 de-represses pho1 expression: evidence that Erh1 is a negative regulator of prt lncRNA termination
Fission yeast Erh1 exists in a complex with RNA-binding protein Mmi1. Deletion of erh1 up-regulates the phosphate homeostasis gene pho1, which is normally repressed by transcription in cis of a 5′ flanking prt lncRNA. Here we present evidence that de-repression of pho1 by erh1Δ is achieved through p...
Autores principales: | Schwer, Beate, Sanchez, Ana M., Shuman, Stewart |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7491324/ https://www.ncbi.nlm.nih.gov/pubmed/32546512 http://dx.doi.org/10.1261/rna.076463.120 |
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