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Nuclease-mediated depletion biases in ribosome footprint profiling libraries
Ribosome footprint profiling is a high-throughput sequencing–based technique that provides detailed and global views of translation in living cells. An essential part of this technology is removal of unwanted, normally very abundant, ribosomal RNA sequences that dominate libraries and increase seque...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7491325/ https://www.ncbi.nlm.nih.gov/pubmed/32503920 http://dx.doi.org/10.1261/rna.075523.120 |