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Allosteric regulation of U1 snRNP by splicing regulatory proteins controls spliceosomal assembly

Alternative splicing is responsible for much of the transcriptomic and proteomic diversity observed in eukaryotes and involves combinatorial regulation by many cis-acting elements and trans-acting factors. SR and hnRNP splicing regulatory proteins often have opposing effects on splicing efficiency d...

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Detalles Bibliográficos
Autores principales: Shenasa, Hossein, Movassat, Maliheh, Forouzmand, Elmira, Hertel, Klemens J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7491332/
https://www.ncbi.nlm.nih.gov/pubmed/32522889
http://dx.doi.org/10.1261/rna.075135.120