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ARF‐AID: A Rapidly Inducible Protein Degradation System That Preserves Basal Endogenous Protein Levels

Inducible degron systems are widely used to specifically and rapidly deplete proteins of interest in cell lines and organisms. An advantage of inducible degradation is that the biological system under study remains intact and functional until perturbation, a feature that necessitates that the endoge...

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Detalles Bibliográficos
Autores principales: Sathyan, Kizhakke Mattada, Scott, Thomas G., Guertin, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7491365/
https://www.ncbi.nlm.nih.gov/pubmed/32757370
http://dx.doi.org/10.1002/cpmb.124