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ARF‐AID: A Rapidly Inducible Protein Degradation System That Preserves Basal Endogenous Protein Levels
Inducible degron systems are widely used to specifically and rapidly deplete proteins of interest in cell lines and organisms. An advantage of inducible degradation is that the biological system under study remains intact and functional until perturbation, a feature that necessitates that the endoge...
Autores principales: | Sathyan, Kizhakke Mattada, Scott, Thomas G., Guertin, Michael J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7491365/ https://www.ncbi.nlm.nih.gov/pubmed/32757370 http://dx.doi.org/10.1002/cpmb.124 |
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