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Enhanced SARS-CoV-2 Neutralization by Secretory IgA in vitro

SARS-CoV-2 primarily infects cells at mucosal surfaces. Serum neutralizing antibody responses are variable and generally low in individuals that suffer mild forms of the illness. Although potent IgG antibodies can neutralize the virus, less is known about secretory antibodies such as IgA that might...

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Detalles Bibliográficos
Autores principales: Wang, Zijun, Lorenzi, Julio C. C., Muecksch, Frauke, Finkin, Shlomo, Viant, Charlotte, Gaebler, Christian, Cipolla, Melissa, Hoffman, Hans-Heinrich, Oliveira, Thiago Y., Oren, Deena A., Ramos, Victor, Nogueira, Lilian, Michailidis, Eleftherios, Robbiani, Davide F., Gazumyan, Anna, Rice, Charles M., Hatziioannou, Theodora, Bieniasz, Paul D., Caskey, Marina, Nussenzweig, Michel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7491508/
https://www.ncbi.nlm.nih.gov/pubmed/32935095
http://dx.doi.org/10.1101/2020.09.09.288555