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Exploratory neuroimmune profiling identifies CNS-specific alterations in COVID-19 patients with neurological involvement

One third of COVID-19 patients develop significant neurological symptoms, yet SARS-CoV-2 is rarely detected in central nervous system (CNS) tissue, suggesting a potential role for parainfectious processes, including neuroimmune responses. We therefore examined immune parameters in cerebrospinal flui...

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Detalles Bibliográficos
Autores principales: Song, Eric, Bartley, Christopher M., Chow, Ryan D., Ngo, Thomas T., Jiang, Ruoyi, Zamecnik, Colin R., Dandekar, Ravi, Loudermilk, Rita P., Dai, Yile, Liu, Feimei, Hawes, Isobel A., Alvarenga, Bonny D., Huynh, Trung, McAlpine, Lindsay, Rahman, Nur-Taz, Geng, Bertie, Chiarella, Jennifer, Goldman-Israelow, Benjamin, Vogels, Chantal B.F., Grubaugh, Nathan D., Casanovas-Massana, Arnau, Phinney, Brett S., Salemi, Michelle, Alexander, Jessa, Gallego, Juan A., Lencz, Todd, Walsh, Hannah, Lucas, Carolina, Klein, Jon, Mao, Tianyang, Oh, Jieun, Ring, Aaron, Spudich, Serena, Ko, Albert I., Kleinstein, Steven H., DeRisi, Joseph L., Iwasaki, Akiko, Pleasure, Samuel J., Wilson, Michael R., Farhadian, Shelli F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7491516/
https://www.ncbi.nlm.nih.gov/pubmed/32935102
http://dx.doi.org/10.1101/2020.09.11.293464