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Longitudinal immune profiling of mild and severe COVID-19 reveals innate and adaptive immune dysfunction and provides an early prediction tool for clinical progression

With a rising incidence of COVID-19-associated morbidity and mortality worldwide, it is critical to elucidate the innate and adaptive immune responses that drive disease severity. We performed longitudinal immune profiling of peripheral blood mononuclear cells from 45 patients and healthy donors. We...

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Detalles Bibliográficos
Autores principales: Rendeiro, André F., Casano, Joseph, Kyriakos Vorkas, Charles, Singh, Harjot, Morales, Ayana, DeSimone, Robert A., Ellsworth, Grant B., Soave, Rosemary, Kapadia, Shashi N., Saito, Kohta, Brown, Christopher D., Hsu, JingMei, Kyriakides, Christopher, Chiu, Steven, Cappelli, Luca, Teresa Cacciapuoti, Maria, Tam, Wayne, Galluzzi, Lorenzo, Simonson, Paul D., Elemento, Olivier, Salvatore, Mirella, Inghirami, Giorgio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7491529/
https://www.ncbi.nlm.nih.gov/pubmed/32935114
http://dx.doi.org/10.1101/2020.09.08.20189092