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Longitudinal immune profiling of mild and severe COVID-19 reveals innate and adaptive immune dysfunction and provides an early prediction tool for clinical progression
With a rising incidence of COVID-19-associated morbidity and mortality worldwide, it is critical to elucidate the innate and adaptive immune responses that drive disease severity. We performed longitudinal immune profiling of peripheral blood mononuclear cells from 45 patients and healthy donors. We...
Autores principales: | Rendeiro, André F., Casano, Joseph, Kyriakos Vorkas, Charles, Singh, Harjot, Morales, Ayana, DeSimone, Robert A., Ellsworth, Grant B., Soave, Rosemary, Kapadia, Shashi N., Saito, Kohta, Brown, Christopher D., Hsu, JingMei, Kyriakides, Christopher, Chiu, Steven, Cappelli, Luca, Teresa Cacciapuoti, Maria, Tam, Wayne, Galluzzi, Lorenzo, Simonson, Paul D., Elemento, Olivier, Salvatore, Mirella, Inghirami, Giorgio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7491529/ https://www.ncbi.nlm.nih.gov/pubmed/32935114 http://dx.doi.org/10.1101/2020.09.08.20189092 |
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