Mitofusin 2 regulates neutrophil adhesive migration and the actin cytoskeleton

Neutrophils rely on glycolysis for energy production. How mitochondria regulate neutrophil function is not fully understood. Here, we report that mitochondrial outer membrane protein Mitofusin 2 (MFN2) regulates neutrophil homeostasis and chemotaxis in vivo. Mfn2-deficient neutrophils are released f...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Wenqing, Hsu, Alan Y., Wang, Yueyang, Syahirah, Ramizah, Wang, Tianqi, Jeffries, Jacob, Wang, Xu, Mohammad, Haroon, Seleem, Mohamed N., Umulis, David, Deng, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7491649/
https://www.ncbi.nlm.nih.gov/pubmed/32788232
http://dx.doi.org/10.1242/jcs.248880

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7491649/
https://www.ncbi.nlm.nih.gov/pubmed/32788232
http://dx.doi.org/10.1242/jcs.248880

Ejemplares similares