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GATA3 suppresses human fibroblasts-induced metastasis of clear cell renal cell carcinoma via an anti-IL6/STAT3 mechanism

Tumorigenesis and metastasis depend on intricate interactions between genetically altered tumor cells and their surrounding microenvironment. It is, however, unclear regarding the molecular mechanisms underlying the progress and metastasis of human clear-cell renal cell carcinoma in the microenviron...

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Detalles Bibliográficos
Autores principales: Shi, Qianqian, Xu, Renfang, Song, Guanglai, Lu, Hao, Xue, Dong, He, Xiaozhou, Xia, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7492134/
https://www.ncbi.nlm.nih.gov/pubmed/31636361
http://dx.doi.org/10.1038/s41417-019-0146-2