Age and life expectancy clocks based on machine learning analysis of mouse frailty

The identification of genes and interventions that slow or reverse aging is hampered by the lack of non-invasive metrics that can predict the life expectancy of pre-clinical models. Frailty Indices (FIs) in mice are composite measures of health that are cost-effective and non-invasive, but whether t...

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Detalles Bibliográficos
Autores principales: Schultz, Michael B., Kane, Alice E., Mitchell, Sarah J., MacArthur, Michael R., Warner, Elisa, Vogel, David S., Mitchell, James R., Howlett, Susan E., Bonkowski, Michael S., Sinclair, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7492249/
https://www.ncbi.nlm.nih.gov/pubmed/32934233
http://dx.doi.org/10.1038/s41467-020-18446-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7492249/
https://www.ncbi.nlm.nih.gov/pubmed/32934233
http://dx.doi.org/10.1038/s41467-020-18446-0

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