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Molecular mechanisms underlying AMH elevation in hyperoestrogenic states in males

Anti-Müllerian hormone (AMH) is secreted by Sertoli cells of the testes from early fetal life until puberty, when it is downregulated by androgens. In conditions like complete androgen insensitivity syndrome (CAIS), AMH downregulation does not occur and AMH increases at puberty, due in part to folli...

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Detalles Bibliográficos
Autores principales: Valeri, Clara, Lovaisa, María M., Racine, Chrystèle, Edelsztein, Nadia Y., Riggio, Marina, Giulianelli, Sebastián, Venara, Marcela, Bedecarrás, Patricia, Ballerini, María G., di Clemente, Nathalie, Lamb, Caroline A., Schteingart, Helena F., Rey, Rodolfo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7492256/
https://www.ncbi.nlm.nih.gov/pubmed/32934281
http://dx.doi.org/10.1038/s41598-020-71675-7