Acyl-CoA thioesterase 1 prevents cardiomyocytes from Doxorubicin-induced ferroptosis via shaping the lipid composition

In this study, we first established the doxorubicin-induced cardiotoxicity (DIC) model with C57BL/6 mice and confirmed cardiac dysfunction with transthoracic echocardiography examination. RNA-sequencing was then performed to explore the potential mechanisms and transcriptional changes in the process...

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Detalles Bibliográficos
Autores principales: Liu, Yunchang, Zeng, Liping, Yang, Yong, Chen, Chen, Wang, Daowen, Wang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7492260/
https://www.ncbi.nlm.nih.gov/pubmed/32934217
http://dx.doi.org/10.1038/s41419-020-02948-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7492260/
https://www.ncbi.nlm.nih.gov/pubmed/32934217
http://dx.doi.org/10.1038/s41419-020-02948-2

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