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Fewer tumour-specific PD-1(+)CD8(+) TILs in high-risk “Infiltrating” HPV(−) HNSCC

BACKGROUND: The prognosis of HPV(-) HNSCC was worse than that of HPV(+) HNSCC. Analysis of tumours and tumour-infiltrating lymphocytes (TILs) may provide insight into the progression of HPV(−) HNSCC. METHODS: The tumour and TIL phenotypic characteristics of 134 HNSCC specimens (HPV(−) tumours were c...

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Detalles Bibliográficos
Autores principales: Xu, Ke, Fu, You, Han, Yong, Xia, Ronghui, Xu, Shengming, Duan, Shengzhong, Zhang, Zhiyuan, Li, Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7492364/
https://www.ncbi.nlm.nih.gov/pubmed/32616847
http://dx.doi.org/10.1038/s41416-020-0966-8