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An effective peptide vaccine strategy circumventing clonal MHC heterogeneity of murine myeloid leukaemia

BACKGROUND: Therapeutic cancer vaccines are an attractive approach for treating malignant tumours, and successful tumour eradication depends primarily on controlling tumour immunosuppression status as well as heterogeneity of tumour cells driven by epigenetic alterations. METHODS: Peptide-loaded den...

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Detalles Bibliográficos
Autores principales: Shin, A-Ri, Lee, Sang-Eun, Choi, Haeyoun, Sohn, Hyun-Jung, Cho, Hyun-Il, Kim, Tai-Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7492404/
https://www.ncbi.nlm.nih.gov/pubmed/32595211
http://dx.doi.org/10.1038/s41416-020-0955-y