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HGF-MET Signaling Shifts M1 Macrophages Toward an M2-Like Phenotype Through PI3K-Mediated Induction of Arginase-1 Expression

Backgrounds and Aims: Hepatocyte Growth Factor (HGF)-MET signaling is known to promote biological functions such as cell survival, cell motility, and cell proliferation. However, it is unknown if HGF-MET alters the macrophage phenotype. In this study, we aimed to study the effects of HGF-MET signali...

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Detalles Bibliográficos
Autores principales: Nishikoba, Nao, Kumagai, Kotaro, Kanmura, Shuji, Nakamura, Yuko, Ono, Mayumi, Eguchi, Hiromi, Kamibayashiyama, Tomomi, Oda, Kohei, Mawatari, Seiichi, Tanoue, Shiroh, Hashimoto, Shinichi, Tsubouchi, Hirohito, Ido, Akio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7492554/
https://www.ncbi.nlm.nih.gov/pubmed/32983173
http://dx.doi.org/10.3389/fimmu.2020.02135