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HGF-MET Signaling Shifts M1 Macrophages Toward an M2-Like Phenotype Through PI3K-Mediated Induction of Arginase-1 Expression
Backgrounds and Aims: Hepatocyte Growth Factor (HGF)-MET signaling is known to promote biological functions such as cell survival, cell motility, and cell proliferation. However, it is unknown if HGF-MET alters the macrophage phenotype. In this study, we aimed to study the effects of HGF-MET signali...
Autores principales: | Nishikoba, Nao, Kumagai, Kotaro, Kanmura, Shuji, Nakamura, Yuko, Ono, Mayumi, Eguchi, Hiromi, Kamibayashiyama, Tomomi, Oda, Kohei, Mawatari, Seiichi, Tanoue, Shiroh, Hashimoto, Shinichi, Tsubouchi, Hirohito, Ido, Akio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7492554/ https://www.ncbi.nlm.nih.gov/pubmed/32983173 http://dx.doi.org/10.3389/fimmu.2020.02135 |
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