CD4(+) T Cell-Mimicking Nanoparticles Broadly Neutralize HIV-1 and Suppress Viral Replication through Autophagy

Therapeutic strategies that provide effective and broad‐spectrum neutralization against HIV-1 infection are highly desirable. Here, we investigate the potential of nanoengineered CD4(+) T cell membrane-coated nanoparticles (TNP) to neutralize a broad range of HIV-1 strains. TNP displayed outstanding...

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Detalles Bibliográficos
Autores principales: Zhang, Gang, Campbell, Grant R., Zhang, Qiangzhe, Maule, Erin, Hanna, Jonathan, Gao, Weiwei, Zhang, Liangfang, Spector, Stephen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7492730/
https://www.ncbi.nlm.nih.gov/pubmed/32934078
http://dx.doi.org/10.1128/mBio.00903-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7492730/
https://www.ncbi.nlm.nih.gov/pubmed/32934078
http://dx.doi.org/10.1128/mBio.00903-20

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