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CD4(+) T Cell-Mimicking Nanoparticles Broadly Neutralize HIV-1 and Suppress Viral Replication through Autophagy
Therapeutic strategies that provide effective and broad‐spectrum neutralization against HIV-1 infection are highly desirable. Here, we investigate the potential of nanoengineered CD4(+) T cell membrane-coated nanoparticles (TNP) to neutralize a broad range of HIV-1 strains. TNP displayed outstanding...
Autores principales: | Zhang, Gang, Campbell, Grant R., Zhang, Qiangzhe, Maule, Erin, Hanna, Jonathan, Gao, Weiwei, Zhang, Liangfang, Spector, Stephen A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7492730/ https://www.ncbi.nlm.nih.gov/pubmed/32934078 http://dx.doi.org/10.1128/mBio.00903-20 |
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