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MARCH8 Inhibits Ebola Virus Glycoprotein, Human Immunodeficiency Virus Type 1 Envelope Glycoprotein, and Avian Influenza Virus H5N1 Hemagglutinin Maturation

Membrane-associated RING-CH-type 8 (MARCH8) strongly blocks human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein (Env) incorporation into virions by downregulating its cell surface expression, but the mechanism is still unclear. We now report that MARCH8 also blocks the Ebola virus (EBO...

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Detalles Bibliográficos
Autores principales: Yu, Changqing, Li, Sunan, Zhang, Xianfeng, Khan, Ilyas, Ahmad, Iqbal, Zhou, Yulong, Li, Shuo, Shi, Jing, Wang, Yu, Zheng, Yong-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7492737/
https://www.ncbi.nlm.nih.gov/pubmed/32934085
http://dx.doi.org/10.1128/mBio.01882-20