Mechanistic Understanding Enables the Rational Design of Salicylanilide Combination Therapies for Gram-Negative Infections

One avenue to combat multidrug-resistant Gram-negative bacteria is the coadministration of multiple drugs (combination therapy), which can be particularly promising if drugs synergize. The identification of synergistic drug combinations, however, is challenging. Detailed understanding of antibiotic...

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Detalles Bibliográficos
Autores principales: Copp, Janine N., Pletzer, Daniel, Brown, Alistair S., Van der Heijden, Joris, Miton, Charlotte M., Edgar, Rebecca J., Rich, Michelle H., Little, Rory F., Williams, Elsie M., Hancock, Robert E. W., Tokuriki, Nobuhiko, Ackerley, David F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7492738/
https://www.ncbi.nlm.nih.gov/pubmed/32934086
http://dx.doi.org/10.1128/mBio.02068-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7492738/
https://www.ncbi.nlm.nih.gov/pubmed/32934086
http://dx.doi.org/10.1128/mBio.02068-20

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