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Castanospermine reduces Zika virus infection-associated seizure by inhibiting both the viral load and inflammation in mouse models

Zika virus (ZIKV) outbreaks have been reported worldwide, including a recent occurrence in Brazil where it spread rapidly, and an association with increased cases of microcephaly was observed in addition to neurological issues such as GBS that were reported during previous outbreaks. Following infec...

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Detalles Bibliográficos
Autores principales: Tharappel, Anil M., Cheng, Yichen, Holmes, Eric H., Ostrander, Gary K., Tang, Hengli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7492813/
https://www.ncbi.nlm.nih.gov/pubmed/32949636
http://dx.doi.org/10.1016/j.antiviral.2020.104935