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Downregulated Recycling Process but Not De Novo Synthesis of Glutathione Limits Antioxidant Capacity of Erythrocytes in Hypoxia

Red blood cells (RBCs) are susceptible to sustained free radical damage during circulation, while the changes of antioxidant capacity and regulatory mechanism of RBCs under different oxygen gradients remain unclear. Here, we investigated the changes of oxidative damage and antioxidant capacity of RB...

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Detalles Bibliográficos
Autores principales: Wang, Yueming, Zhao, Nannan, Xiong, Yanlei, Zhang, Jiashen, Zhao, Dongmei, Yin, Yancun, Song, Lele, Yin, Yipeng, Wang, Jing, Luan, Xiying, Xiong, Yanlian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7492869/
https://www.ncbi.nlm.nih.gov/pubmed/32963701
http://dx.doi.org/10.1155/2020/7834252