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Inhibition of Macrophage Migration Inhibitory Factor Protects against Inflammation through a Toll-like Receptor-Related Pathway after Diffuse Axonal Injury in Rats

OBJECTIVE: We have previously demonstrated that inflammation induced by toll-like receptors (TLRs) 2/4 exert cerebral deleterious effects after diffuse axonal injury (DAI); however, the underlying mechanisms are not fully understood. Macrophage migration inhibitory factor (MIF) is a multifunctional...

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Detalles Bibliográficos
Autores principales: Zhao, Yonglin, Wei, Xing, Li, Weimiao, Shan, Changyou, Song, Jinning, Zhang, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7492939/
https://www.ncbi.nlm.nih.gov/pubmed/32964038
http://dx.doi.org/10.1155/2020/5946205