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Deletion of Bmal1 Impairs Pancreatic β-Cell Function via Mitochondrial Signaling Pathway
Several studies have demonstrated that brain and muscle Arnt-like protein-1 (Bmal1) acts as a core clock gene for maintaining normal cell function, including hepatocytes and cardiomyocytes. Loss of Bmal1 is associated with type 2 diabetes due to pancreatic β-cell failure. However, little information...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Hindawi
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7492957/ https://www.ncbi.nlm.nih.gov/pubmed/32964049 http://dx.doi.org/10.1155/2020/9803024 |