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RIG-I Promotes Cell Death in Hepatocellular Carcinoma by Inducing M1 Polarization of Perineal Macrophages Through the RIG-I/MAVS/NF-κB Pathway

BACKGROUND: The development and metastasis of cancer cells are regulated by tumor-associated macrophages (TAMs) present in the surrounding tumor microenvironment. RIG-I is a key pathogen recognition receptor against RNA viruses that regulates innate immunity in cancer progression. Till now, the mech...

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Detalles Bibliográficos
Autores principales: Zhou, Bei, Li, Cuiping, Yang, Yun, Wang, Zhuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493023/
https://www.ncbi.nlm.nih.gov/pubmed/32982277
http://dx.doi.org/10.2147/OTT.S258450