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RIG-I Promotes Cell Death in Hepatocellular Carcinoma by Inducing M1 Polarization of Perineal Macrophages Through the RIG-I/MAVS/NF-κB Pathway

BACKGROUND: The development and metastasis of cancer cells are regulated by tumor-associated macrophages (TAMs) present in the surrounding tumor microenvironment. RIG-I is a key pathogen recognition receptor against RNA viruses that regulates innate immunity in cancer progression. Till now, the mech...

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Detalles Bibliográficos
Autores principales:	Zhou, Bei, Li, Cuiping, Yang, Yun, Wang, Zhuo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493023/ https://www.ncbi.nlm.nih.gov/pubmed/32982277 http://dx.doi.org/10.2147/OTT.S258450

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